Potential for long-term relief.
An exciting, minimally invasive urethral stricture treatment, the Optilume drug-coated balloon was developed in response to severe patient and physician dissatisfaction with current stricture solutions.
This proprietary technology combines balloon dilation and drug delivery, and is well-tolerated by patients. Rapid uptake of the highly lipophilic drug, paclitaxel, limits hyperactive cell proliferation and the fibrotic scar tissue generation that results in stricture recurrence. Learn more »
How it works.
The Optilume procedure is similar to traditional mechanical dilation method, making it easy to learn and perform. The semi-compliant balloon expands into the tissue, creating micro-fissures which facilitate circumferential drug absorption.
Balloon inflates to create micro-fissures in the tissue, providing a pathway for drug absorption.
Hydrophillic coating facilitates rapid release of paclitaxel.
Hydrophobic and lipophilic properties support rapid celluar uptake—enabling the drug to pass through the urethral wall and take up residency in the tissue.Read "How I Do It", Dean S. Elterman, MD »
By combining a simple, effective balloon dilation with localized delivery of a proven antiproliferative —Optilume aims to provide long-term relief from stricture recurrence.
The semi-compliant inflatable balloon expands to create micro-fissures in the tissue, facilitating drug absorption
A novel excipient molecularly binds paclitaxel to the balloon until the balloon inflates and dilates the tissue for rapid, controlled drug release.
Travels easily over the guidewire and can cross tight strictures
- Ends the high recurrence cycle of failed endoscopic stricture management
- Minimally invasive
- Compatible with flexible cystoscopes for maximum patient comfort
- Balloon dynamic compliance provides optimal expansion for urology applications
“We're optimistic that the drug-coated balloon catheter will dramatically improve the quality of life of men suffering daily from the symptoms of urethral strictures.”
Urology of Virginia